Maurizio Sarri’s Chelsea welcome a former favourite in Frank Lampard to Stamford Bridge on Wednesday night.
The Rams travel to London with a place in the quarter-finals of the Carabao Cup at stake.
With the Blues aiming to compete on all four fronts this season, extra onus falls on Sarri to rotate his team and make the best use of the squad he has at his disposal.
This is the XI that we think you could see at Stamford Bridge on Wednesday night.
GK - Willy Caballero
The experienced Argentinian deserves a chance in the cups, having not featured in the Europa League as expected.
RB - Davide Zappacosta
Another who has found game time hard to come by, but the Italian could start on Wednesday, with Cesar Azpilicueta dropping to the bench.
CB - Gary Cahill
Looks like his Chelsea days are numbered, but he’ll be keen to put in a good performance against his old team-mate.
CB - Andreas Christensen
Andreas Christensen’s father has talked up the need for game time in the immediate future and that could come against Derby.
LB - Emerson
Chances have been few and far between for Emerson this season, but he could get a chance to impress against the Rams.
CM - Cesc Fabregas
Fabregas could come into the team to give Jorginho another rest ahead of Sunday’s game against Crystal Palace.
CM - Ruben Loftus-Cheek
Enjoying a good run in the team and another start on Wednesday will do him the world of good.
CM - Mateo Kovacic
Kovacic missed out on a starting spot on Sunday and some game time on Wednesday night will keep him on his toes.
RW - Victor Moses
The Derby tie presents an opportunity to give some game time to the Nigerian.
LW - Willian
The Brazilian is likely to keep his place in the team with both Eden Hazard ruled out and Pedro a confirmed as a doubt for the midweek clash.
ST - Alvaro Morata
Olivier Giroud is a doubt for the game which may mean that Morata is forced to start once again for the Blues.
He’ll head into the game with more confidence behind him after his goal on Sunday.